E-ISSN 2223-0343

Effect of sidr honey on healing of contaminated wounds in alloxan-induced diabetes mellitus in dogs

Musa A. Alshehabat*1, Zuhair A. Bani Ismail1, Wael M. Hananeh2, and Mofleh S. Awawdeh2

1Department of Veterinary Clinical Sciences; 2Department of Pathology and Public Health, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan


The objective of the study was to compare Sidr honey and iodine on healing of contaminated wounds in induced diabetes in dogs. Diabetes mellitus was induced in dogs (n=4) using intravenous injection of 120 mg/kg alloxan monohydrate. Status of the diabetes was verified using oral glucose tolerance test. Four (1.5 cm x 1.5 cm) wounds were created on each of the research subject’s back. Wounds were covered with 2 gm of dog feces under a bandage for 24 hours prior to starting the treatments. In each of the diabetic dogs or control dogs (n=4), 2 wounds (n=8) were treated with 1-2 ml of 10% povidine iodine and 2 wounds (n=8) were treated with 1-2ml of pure Sidr honey. Treatments started twice daily for the first week and then once daily for the rest of the study. Wounds were left to heal by second intention healing. Healthy control dogs were treated in a similar fashion. Wounds in the alloxan-induced diabetic dogs healed at a slower rate. In both groups, honey or iodine treated wounds appeared to heal at a comparable rate. Sidr honey can be considered as a safe natural remedy to manage contaminated wounds.

Keywords: Dogs; alloxan; contaminated; wounds; Sidr
To cite this article: Alshehabat MA, ZAB Ismail, WM Hananeh and MS Awawdeh, 2016. Effect of sidr honey on healing of contaminated wounds in alloxan-induced diabetes mellitus in dogs. Res. Opin. Anim. Vet. Sci., 6(8): 242-247.

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