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Effects of hitchner b1 vaccine antibodies on organ distribution,
persistence and shedding of velogenic Newcastle Disease Virus (kudu 113)
in chickens
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Emmanuel Chukwudi Okwor1, Didacus Chukwuemeka Eze1,
George O.N Echeonwu2, John Okpabi Ibu3, Paul
Chekwube Eze1 and John Osita Okoye1 |
1Department
of Veterinary Pathology and Microbiology, University of Nigeria, Nsukka;
2Virology Department, Federal College of Veterinary and
Medical Laboratory Technology, National Veterinary Research Institute,
Vom, Plateau State, Nigeria, 3Department of Veterinary
Pathology and Microbiology, Federal University of Agriculture, Makurdi,
Nigeria
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Abstract |
Newcastle disease (ND)
is endemic in Nigeria. Control is by vaccination and one of the
commonly used vaccines against the disease is Hitchner B1 vaccine. Kudu
113 virus is a velogenic strain of Newcastle disease virus (NDV) that
have been characterised. ND is very common among vaccinated flocks with
rapid spread or transmission. This study evaluated the effects of
Hichner B1 induced humoral antibody response on the Kudu 113 viral
distribution, persistence and excretion from experimentally infected
chickens. Four hundred chickens were procured at day old and randomly
assigned into three groups: unvaccinated and unchallenged (G1),
unvaccinated and challenged (G2) and vaccinated and challenged (G3).
Vaccination was done on day 2 of age and batches of birds in G2 and G3
were taken at specified intervals for challenge. Virus distribution and
persistence in organs and shedding in the faeces of the infected birds
were assessed by isolation studies and quantitative haemagglutination
assay. Vaccination did not prevent viral replication but significantly
reduced the distribution and shedding of Kudu 113. Peak distribution and
shedding was seen between days 4 and 7 post challenge (PC) and virus
persisted in the faeces of infected birds for a maximum of 21 days.
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Keywords:
Hitchner B1; Kudu 113 virus; chickens; distribution; virus shedding |
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To cite this article:
Okwor EC, DC Eze, GON Echeonwu, JO Ibu, PC Eze and JO Okoye,
2015.
Effects of hitchner b1 vaccine antibodies on organ distribution,
persistence and shedding of velogenic Newcastle Disease Virus (Kudu 113)
in chickens.
Res.
Opin. Anim. Vet. Sci., 5(8): 335-341. |
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