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Caroli's syndrome in a Shami goat

Wael Hananeh* and Najib Faizee

Veterinary Pathology Laboratory, Department of Pathology and Animal Health, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid, PO Box 3030, Jordan


Caroli's syndrome is a congenital hepatic disorder that is characterized by multifocal, segmental dilatation of large intrahepatic bile ducts and congenital hepatic fibrosis. Diagnosis of Caroli’s syndrome with polycystic kidney disease was made in a Shami goat kid based on the gross and histopathology of the hepatorenal lesions. Grossly, the liver was enlarged and diffusely greenish with pinpoint whitish foci. Both kidneys exhibited multiple renal cysts. Histopathologically, the liver exhibited multifocal hepatic fibrosis, bile duct ectasia and hyperplasia that were associated with diffuse cystic dilatation of medullary renal tubules of both kidneys. These hepatorenal lesions resemble Caroli’s syndrome in human. To the best of our knowledge, this is the first report of Caroli’s syndrome in a Shami goat.

Keywords: Caroli's syndrome; congenital hepatic fibrosis; polycystic kidney; goat
To cite this article: Hananeh W and N Faizee, 2014. Caroli's syndrome in a Shami goat. Res. Opin. Anim. Vet. Sci., 4(7): 382-384.

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