The present study was conducted to assess the effect of short term starvation on galanin, leptin, thyroid hormones, insulin, prolactin, growth hormone, ghrelin and factors involved in energy metabolism including high-density lipoprotein (HDL), cholesterol, β-hydroxybutyrate, glucose, non-esterified fatty acids (NEFA), triglyceride (TG) and very-low-density lipoprotein (VLDL) concentrations in adult goats. Eight non-lactating non-pregnant goats aged 4-5 years and body condition score (BCS) 3 were randomly assigned to control and test groups. The animals were trained to eat their daily forage ration during a period of 10 days. The experimental procedure was applied for 3 days during which control group received 120% of maintenance energy, while the test group was supplied with 60% of maintenance energy. Blood samples were collected on days 8 and 10 and at 2, 12, 24, 36 and 72 hours after beginning of starvation. Blood parameters were measured according to standard procedures. No significant differences were observed in the concentrations of cholesterol, fT₃, fT₄, glucose, growth hormone, leptin, VLDL-cholesterol, non-esterified fatty acids (NEFA), triglyceride (TG) and prolactin between control and test groups. A significant difference was found in β-hydroxybutyrate concentration between fed and fasted goats at 36^th hour of starvation. Moreover, there was a significant difference in the concentration of HDL-cholesterol between control and test groups at 72^nd hour (P<0.05). Gradual starvation had no effect on hormonal and neuropeptides concentrations probably.