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PRINT: ISSN 2221-1896
ONLINE : ISSN 2223-0343
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Comparative study on the haematology and persistence of velogenic
Newcastle
disease virus in chickens and guinea fowls |
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A. O. Igwe1, W.S. Ezema2*, J. I. Ibu3,
J. I. Eze4 and J.O.A. Okoye2
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1Department
of Veterinary Pathology, Michael Okpara University
of Agriculture, Umudike, Abia
State,
Nigeria,
2Department
of Veterinary Pathology and Microbiology, University of Nigeria, Nsukka;
3Virology Division, National Veterinary Research Institute,
Vom, Plateau State, Nigeria; 4Department of Veterinary
Medicine, University of Nigeria, Nsukka, Enugu State, Nigeria
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Abstract |
Six weeks old cockerels and guinea fowls were inoculated intramuscularly
with a local Nigerian strain of velogenic
Newcastle
disease virus (VNDV). Thereafter a comparative study of virus isolation
in the tissues, detection in cloacal swabs and haematological changes
were studied. The virus was
isolated more frequently in the lung/trachea of the cockerels than
guinea fowls. But the frequency of isolation from the bursa, thymus,
spleen and brain in the two species was virtually the same. The highest
concentration of the virus occurred in the bursa of the infected
cockerels on days 3 and 6 post infection (PI). No virus was isolated
from the two species after day 15 PI. Suspensions of the cloacal swabs
showed heamagglutination (HA) activity from days 3 to 15 PI. The highest
concentration of the virus was obtained on day 10 PI in both species.The
infection produced no significant changes in the packed cell volume
(PCV), haemoglobin concentration (HbC) and red blood cell (RBC) count in
both species (p>0.05). But the infection in both species produced
leucocytosis, heterophilia and lymphopenia (P<0.05). The above
observations show that despite the fact that the infection is more
severe in the cockerels; the pathogenesis of the infection in both
species is very similar.
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Keywords:
velogenic
Newcastle
disease virus; haematology; guinea fowl; cockerel |
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To cite this article:
Igwe AO, WS Ezema, JI Ibu, JI Eze and JOA Okoye,
2013.
Comparative study on the haematology and persistence of velogenic
newcastle
disease virus in chickens and guinea fowls.
Res.
Opin. Anim. Vet. Sci., 3(5), 136-142. |
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