The aim of the present study was to evaluate the effect of ginger and cumin powders on performance of broiler chicks. A total of 144 day old (Ross 308 broiler) chicks were randomly divided into four groups. Chicks were fed basal diet as control (T1), 0.2% ginger (T2) and 0.2% cumin (T3) powder. At the end of the trial, four birds form each treatment were slaughtered. Feed intake, body weight gain, feed conversion ratio (FCR) and visceral organs were investigated. Some haematological parameters such as calcium (Ca), phosphorus (P), cholesterol, triglycerides and antibody titre against Newcastle vaccine were also evaluated. Data showed that feed intake and body weight  gain increased significantly in T2 and T3 in comparison to control (P<0.05). FCR improved significantly in T3 compared to T1 and T2. Percentage weight of abdominal fat and Bursa of fabricuous decreased significantly in T3. Percentage weight of spleen, gizzard and carcass yield increased significantly in T3. However, percentage weight of liver and heart increased significantly in T2. Cholesterol profile decreased significantly in experimental groups compared to control. Serum Ca increased significantly in T3 and P concentration decreased significantly in T2 groups. Antibody titre increased significantly in treated groups measured at 35 and 42 days. In conclusion, it seems that ginger and cumin powder in the feed at level of 0.2% has significant effect on performance and blood biochemistry in broiler.