This experiment was aimed to determine the chemical composition of the rice gluten meal (RGM) and the effect of its feeding on the growth performance, some blood parameters, nutrient digestibility and carcass characteristics of broiler chickens as an alternative to corn gluten meal and soybean meal. Ross 308 one-day old broiler chicks (n = 300) were randomly divided into six experimental groups, receiving diets containing rice gluten meal with six different inclusion levels (0, 2.5, 5.0, 7.5, 10 and 12.5%) for 42 days. The experimental diets were formulated from maize, soybean meal, corn gluten meal and/or rice gluten meal and vegetable oil. All diets were isoenergetic and isonitrogenous. Titanium dioxide (TiO₂) was incorporated in the finisher period into each diet at a rate of 5 g/kg as an indigestible marker to enable assessment of nutrient digestibility (dry matter (DM), crude protein (CP), ether extract (EE), neutral detergent fiber (NDF) and starch). Growth performance parameters like body weight (BW), body weight gain (BWG), feed intake (FI) and feed conversion ratio (FCR) were monitored weekly. At 42 days of age, blood samples were collected and serum was separated for determination of serum lipid profile, glucose, total protein, albumin and globulin. Five birds from each treatment were slaughtered on day 42, for measuring the carcass dressing percentage, and internal organ weights. Results showed that birds fed rice gluten meal with different inclusion rates up to 12.5% have had the same performance parameters like the control diet and there was no significant difference between the different treatments in BW, BWG, FI and FCR. Serum lipid profile, glucose, total protein, albumin and globulin of the different treatment were within the normal range and did not affected by increasing the level of rice gluten meal up to 12.5%. There were no differences in the dressing percentage and internal organs among treatments. Digestibility of DM, CP, EE, NDF and starch were similar across different treatments without any significant differences. In conclusion, birds fed the rice gluten diets compared well with those fed the control for growth performance, carcass dressing and nutrient digestibility and can be included in the broiler diet up to 12.5% without any adverse effect.