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PRINT: ISSN 2221-1896
ONLINE : ISSN 2223-0343
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A case of ovarian remnant syndrome with cystic papillary hyperplasia in
a queen: clinicopathological evaluation and
expressions of eostrogen and progesteron receptors, uroplakins and
transforming growth factor-β1
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Mehmet Eray Alcigir*1, Kubra Karakas2, Halit Kanca2,
Hasan Alkan2, Sevil Atalay Vural1 and Arda Selin
Tunc1 |
1Department
of Pathology; 2Department of Obstetrics and Gynecology,
Faculty of Veterinary Medicine, Ankara University, 06110, Diskapi,
Ankara, Turkey
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Abstract |
Ovarian Remnant Syndrome (ORS) is a gynecopathological disorder in which
eostrus and pseudopregnancy like signs are observed after ovarioectomy
or ovariohysterectomy (OHE) in animals. The syndrome is generally
occurred due to iatrogenic failure, in which both ovaries are not
completly removed, especially ovarian cortex, in surgical operations. In
this case, in a 1½ year old mix breed cat showed typical estrous signs.
Cornified vaginal epithelial cells were seen in cytological examination.
Eostrodiol-progesteron levels were measured as 52.3 pg/ml and 0.311 ng/ml
respectively. After operation,
biopsy was performed. Papillary formations were detected in lumin of
cystic structure of the remnant ovary. In immunohistochemistry, mild to
moderate positive reactions were obtained from ER (eostrogen receptor),
PR (progesteron receptor) and Uroplakin-10 (URO-10) in epithelial cells
lining papillary extentions although mild positive reactions were
obtained from Transforming Growth Factor-β1 (TGF- β1). URO-10 was also
mild in epithelial cells lining follicle like structures. URO-9 did not
give any positive reaction. According to the avaialable literature, this
is the first study which reported ORS with particular finidngs of
immunohistochemical technique.
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Keywords:
Cat; ovarian remnant syndrome; clinicopathology; immunohistochemistry |
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To cite this article:
Alcigir ME, K Karakas, H Kanca, H Alkan, SA Vural and AS Tunc,
2014.
A case of ovarian remnant syndrome with cystic papillary hyperplasia in
a queen: clinicopathological evaluation and
expressions of eostrogen and progesteron receptors, uroplakins and
transforming growth factor-β1.
Res.
Opin. Anim. Vet. Sci., 4(10): 526-531. |
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