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Effects of cigarette smoking on histology of trachea and lungs of albino
rat |
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Shraideh Ziad1*, Al-Awaida Wajdy2
and Badran Darwish3
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1Department of Biological Sciences, Faculty of
Science, The University of Jordan, Amman, Jordan; 2Department
of Biology and Biotechnology, American University of Madaba, Madaba,
Jordan; 3Department of Anatomy and Histology, Faculty of
Medicine, The University of Jordan,
Amman, Jordan
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Abstract |
This work was an attempt
to reveal the effects of a Jordanian cigarette smoke on albino rat
tissues at the cellular level. Two groups of male albino rats were
exposed to the cigarette smoke for three months on a daily basis, using
a special modified smoking
machine. Exposure of albino rats for 3 months to cigarette smoke
caused drastic histological changes in the tracheal epithelium including
epithelial cells proliferation, disruption of its cilia, and presence of
inclusion bodies. There was a marked thickening in the alveolar wall of
lung alveoli, collapsed alveoli and blood extravasations. These changes
indicate that nicotine induced changes similar to those of chronic
irritation of tissue may decrease the efficiency of gaseous exchange in
alveoli and predispose to neoplastic changes.
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Keywords:
Cigarette smoking;
trachea; lungs; Albino rat |
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To cite this article:
Ziad S, AA Wajdy and B
Darwish, 2013.
Effects of cigarette smoking on histology of trachea
and lungs of albino rat.
Res.
Opin.
Anim. Vet. Sci., 3(10), 356-362. |
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