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Assessment of clinical anesthesia and cardiopulmonary effects of
propofol in detomidine premedicated donkeys
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Howaida M. Abu-Ahmed |
Department of Surgery, Faculty of Veterinary Medicine, Alexandria
University, Egypt
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Abstract |
This study was carried out to evaluate the anesthetic quality and
cardiopulmonary effects of propofol in detomidine premedicated donkeys
underwent castration. Seven clinically healthy donkeys were used; each
one was used in two trials with one week interval. The donkeys in both
trials were sedated by slow i.v injection of 0.04 mg/kg detomidine, 10
minutes later the anesthesia was induced by slow i.v injection of 2
mg/kg propofol. The donkeys were allowed to recover without surgery in
the first trial. One week later the same donkeys were used for the
second trial where after induction the anesthesia was maintained for 30
minutes by i.v infusion of 0.1 mg/kg/min. propofol. The infusion started
10 minutes post detomidine/propofol induction to accomplish castration.
During anesthesia, induction and recovery scores, sleeping and recovery
times, respiratory and heart rates and blood gases were assessed.
Propofol resulted in rapid induction (20-23 seconds) and smooth recovery
with total recumbency period of 29.5
±
3.29 and 100
±
10.24 minutes in the first and second trial, respectively. Respiratory
rate was significantly reduced with significant increase in PCO2
in both trials. Thus, i.v injection of 2mg/kg propofol in detomidine
pre-medicated donkeys provided rapid, excellent induction and smooth
recovery. Maintenance of anesthesia with propofol infusion provided
adequate sedation, analgesia and muscle relaxation for castration in
donkeys with transient cardiopulmonary changes.
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Keywords:
Castration, detomidine, propofol, cardiopulmonary, donkeys |
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To cite this article:
Abu-Ahmed HM,
2014.
Assessment of clinical anesthesia and cardiopulmonary effects of
propofol in detomidine premedicated donkeys.
Res.
Opin. Anim. Vet. Sci., 5(1): 38-42. |
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